For decades, cancer research has focused on the role of genetic mutations, or changes in the DNA sequence, in driving cancer. But DNA sequence is only part of the story. Like mutations in genes, epigenetic changes can also cause cancer. Epigenetics refers to changes in how genetic material is packaged and read by the cell, rather than changes to the DNA itself. We now know these changes can be reversed, opening the door to a new class of cancer-fighting drugs.
Hear from Dana-Farber Cancer Institute’s Chief Scientific Officer Kevin Haigis, PhD, in conversation with Dana-Farber’s Bradley Bernstein, MD, PhD, and Cigall Kadoch, PhD, about the revolutionary science of epigenetics. During their 45-minute discussion and 15-minute question-and-answer session, you will learn how applying epigenetic mechanisms has the potential to inform new treatments in both children and adults with cancer.
To learn more, visit The Revolutionary Science section of this site.