We simply cannot rest on prior successes in our laboratories, our clinics—and our fundraising—and hope that progress will continue apace. Unrestricted gifts of all sizes to The Dana-Farber Campaign’s Defy Cancer Fund will accelerate that success by propelling innovative early stage research; speeding new drugs into clinical trials; retaining and attracting the best researchers, clinicians, and staff; meeting unanticipated needs such as those posed by COVID-19; and ensuring that we are fully serving our patients’ physical, emotional, psychological, and spiritual needs.